Complete list of publications (TEd Lab)
2022
- Rodocker HI and Tedeschi A (2022) Overcoming axon regeneration failure and psychopathology: how may gabapentinoids help boost CNS repair? (in press) Neural Regeneration Research
- Roy D, Myers JM, Tedeschi A (2022) Protocol for assessing ex-vivo lipolysis of murine adipose tissue STAR Protocols DOI: 10.1016/j.xpro.2022.101518
- Rodocker HI*, Bordbar A*, Larson MJE*, Biltz RG, Wangler L, Fadda P, Godbout JP, Tedeschi A (2022) Breaking mental barriers promotes recovery after spinal cord injury Front. Cell. Neurosci. (*Co-first authors) DOI: 10.3389/fnmol.2022.868563
- Tedeschi A, Larson MJE, Zouridakis A, Mo L, Bordbar A, Myers JM, Qin HY, Rodocker HI, Fan F, Lannutti JJ, McElroy CA, Nimjee SM, Peng J, Arnold WD, Moon LDF, Sun W Harnessing cortical plasticity via gabapentinoid administration promotes recovery after stroke Brain https://doi.org/10.1093/brain/awac103
- Eltobgy M, Zani A, Kenney AD, Estfanous S, Kim E, Badr A, Carafice C, Daily K, Whitham O, Pietrzak M, Webb A, Kawahara J, Eddy AC, Denz P, Lu M, Mahesh KC, Peeples ME, Li J, Zhu J, Que J, Robinson R, Mejia OR, Rayner RE, Hall-Stoodley L, Seveau S, Gavrilin MA, Zhang X, Thomas J, Kohlmeier JE, Suthar MS, Oltz E, Tedeschi A, Robledo-Avila FH, Partida-Sanchez S, Hemann EA, Abdelrazik E, Forero A, Nimjee SM, Boyaka PN, Cormet-Boyaka E, Yount JS, Amer AO Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis PNAS https://doiorg/10.1073/pnas.2202012119
- Roy D, Tedeschi A The role of lipids, lipid metabolism and ectopic lipid accumulation in axon growth, regeneration and repair after CNS injury and disease Cells https://doi.org/10.3390/cells10051078
- Presley KF, Fan F, DiRando NM, Shahhosseini M, Rao JZ, Tedeschi A, Castro CE, Lannutti JJ. Injectable, dispersible polysulfone-polysulfone core-shell particles for optical oxygen sensing Journal of Applied Polymer Science https://doi.org/10.1002/app.50603
- Cybyk DB, Reinsch BM, Presley KF, Schweller RM, Tedeschi A, Burns T, Chaparro FJ, Ly JT, Dalton MJ, Lozano M, Grusenmeyer TA, Lannutti JJ. Biodegradable oxygen biosensors via electrospinning. Med. Devices Sens. doi.org/10.1002/mds3.10149.
- Kiyoshi CM, Tedeschi A. Axon growth and synaptic function: A balancing act for axonal regeneration and neuronal circuit formation in CNS trauma and disease. Dev Neurobiol doi: 10.1002/dneu.22780.
- Sun W, Larson MJE, Kiyoshi CM, Annett AJ, Stalker WA, Peng J, Tedeschi A. Gabapentinoid treatment promotes corticospinal plasticity and regeneration following murine spinal cord injury. The Journal of Clinical Investigation doi: 10.1172/JCI130391
- Laredo F, Plebanski J, Tedeschi A. Pericytes: problems and promises for CNS repair. In press Front. Cell. Neurosci.
- Tedeschi A*, Dupraz S*, Curcio M*, Laskowski C*, Schaffran B*, Flynn KC, Santos TE, Stern S, Hilton BJ, Larson MJE, Gurniak CB, Witke W, Bradke F. ADF/Cofilin-mediated actin turnover promotes axon regeneration in the adult CNS. Neuron (*Co-first authors) 103(6):1073-1085.e6. doi: 10.1016/j.neuron.2019.07.007
- Tedeschi A, and Popovich GP. The Application of Omics Technologies to Study Axon Regeneration and CNS Repair. F1000 Faculty Reviews. https://doi.org/10.12688/f1000research.17084.1
- Hilton B, Blanquie O, Tedeschi A and Bradke F. High resolution 3D imaging and analysis of axon regeneration in unsectioned spinal cord with or without tissue clearing. Nat. Protocols 14(4):1235-1260. doi: 10.1038/s41596-019-0140-z
- Sun W, Tedeschi A, and Shi R. Recent developments of regenerative strategies to treat spinal cord injuries. (book chapter) Neurotrauma: A comprehensive textbook on traumatic brain injury and spinal cord injury. Edited by Wang KKW
- Prüss H, Tedeschi A, Thiriot A, Lynch L, Loughhead SM, Stutte S, Mazo IM, Kopp MA, Brommer B, Blex C, Geurtz LC, Liebscher T, Niedeggen A, Dirnagl U, Bradke F, Volz MS, DeVivo MJ, Chen Y, von Andrian UH & Schwab JM. Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex. Nat. Neurosci. 20(11):1549-1559. doi: 10.1038/nn.4643
- Tedeschi A and Bradke F (2016) Spatial and temporal arrangement of neuronal intrinsic and extrinsic mechanisms controlling axon regeneration. Curr Opin Neurobiol. 28;42:118-127. doi: 10.1016/j.conb.2016.12.005
- Tedeschi A*, Omura T*, and Costigan M (2016) CNS repair and axon regeneration: Using genetic variation to determine mechanisms. Exp Neurol. pii: S0014-4886(16)30116-9. doi: 10.1016/j.expneurol.2016.05.004 (* Equal contribution)
- Alecu I, Tedeschi A, Behler N, Wunderling K, Lamberz C, Lauterbach MAR, Gaebler A, Ernst D, Van Veldhoven PP, Al-Amoudi A, Latz E, Othman A, Kuerschner L, Hornemann T, Bradke F, Thiele C, Penno A (2016) Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction. J Lipid Res. pii: jlr.M068676.
- Tedeschi A, Dupraz S, Laskowski CJ, Xue J, Ulas T, Beyer M, Schultze JL, and Bradke F (2016) The calcium channel subunit Alpha2delta2 suppresses axon regeneration in the adult CNS. Neuron 19;92(2):419-434. Cover Article. Faculty 1000 recommended
- Omura T, Omura K, Tedeschi A, Riva P, Painter M, Rojas L, Martin J, Lisi V, Huebner E, Latremoliere A, Yin Y, Barrett L, Singh B, Lee S, Crisman T, Gao F, Li S, Kapur K, Geschwind DH, Kosik KS, Coppola G, He Z, Carmichael ST, Benowitz LI, Costigan M, Woolf CJ (2015) Robust axonal regeneration occurs in the injured CAST/Ei mouse CNS. Neuron 86(5):1215-27.
- Ruschel J, Hellal F*, Flynn KC*, Dupraz S*, Elliot DA, Tedeschi A, Bates M, Sliwinski C, Brook G, Dobrint K, Peitz M, Brüstle O, Norenberg MD, Blesch A, Weidner N, Bunge MB, Bixby JL, Bradke F (2015) Systemic administration of epothilone B promotes axon regeneration after spinal cord injury. Science 348(6232):347-52. (* equal contribution)
- Tedeschi A and Bradke F (2014) A new “spin” on recovery after spinal cord injury. Cell 159(7):1494-6.
- Ni Y*, Nawabi H*, Liu X, Yang L, Miyamichi K, Tedeschi A, Xu B, Wall N, Callaway E and He Z (2014) Characterization of long-descending pre-motor propriospinal neurons in the spinal cord. J. Neurosci. 34(28):9404-17. (* Co-first authors)
- Puttagunta R*, Tedeschi A*, Grando Soria M, Hervera A, Lindner R, Rathore KI, Gaub P, Joshi Y, Nguyen T, Schmandke A, Laskowski CJ, Boutillier AL, Bradke F, and Di Giovanni S (2014) PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system. Nat. Commun. 5:3527 doi:10.1038/ncomms4527 (* Co-first authors)
- Stern S, Haverkamp S, Sinske D, Tedeschi A, Naumann U, Di Giovanni S, Kochanek S, Nordheim A, and Knöll B (2013) The transcription factor serum response factor (SRF) stimulates axon regeneration through cytoplasmic localization and cofilin interaction. J. Neurosci. 33(48):18836-48.
- Tedeschi A and Bradke F (2013) The DLK signalling pathway—a double-edged sword in neural development and regeneration. Embo Rep. 14(7):605-14.
- Floriddia EM, Rathore KI, Tedeschi A, Quadrato G, Wuttke A, Lueckmann JM, Kigerl KA, Popovich PG, Di Giovanni S (2012) p53 Regulates the neuronal intrinsic and extrinsic responses affecting the recovery of motor function following spinal cord injury. J. Neurosci. 32(40):13956-70.
- Tedeschi A (2012) Tuning the orchestra: transcriptional pathways controlling axon regeneration. Front. Mol. Neurosci. 4:60. doi: 10.3389/fnmol.2011.00060.
- Liu K, Tedeschi A, Park KK, and He Z (2011) Neuronal Intrinsic Mechanisms of Axon Regeneration. Annu. Rev. Neurosci. 34:131-52.
- Tedeschi A and He Z (2010) Axon Regeneration: Electrical Silencing is a Condition for Regrowth. Curr. Biol. 20(17):R713-4.
- Gaub P, Tedeschi A, Puttagunta R, Nguyen T, Schmandke A and Di Giovanni S (2010) HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300 and P/CAF-dependent p53 acetylation. Cell Death Differ. 17(9):1392-408.
- Liu K*, Lu Y *, Lee JK, Samara R, Willenberg R, Sears-Kraxberger I, Tedeschi A, Park KK, Jin D, Cai B, Xu B, Connolly L, Steward O, Zheng B and He Z (2010) PTEN deletion enhances the regenerative ability of adult corticospinal neurons. Nat. Neurosci. 13(9):1075-81. (* Co-first authors) Cover article. Faculty 1000 recommended
- Tedeschi A, Nguyen T, Steele SU, Feil S, Naumann U, Feil R and Di Giovanni S (2009) The tumour suppressor p53 transcriptionally regulates cGKI expression during neuronal maturation and is required for cGMP-dependent growth cone collapse. J. Neurosci. 29(48):15155-60.
- Nguyen T, Lindner R, Tedeschi A, Försberg K, Green A, Wuttke A, Gaub P and Di Giovanni S (2009) NFAT-3 is a transcriptional repressor of the growth associated protein 43 during neuronal maturation. J. Biol. Chem. 284(28):18816-23.
- Tedeschi A and Di Giovanni S (2009) The non-apoptotic role of p53 in neuronal biology: enlightening the dark side of the moon. EMBO Rep. 10(6):576-83. Cover review.
- Tedeschi A, Nguyen T, Puttagunta R, Gaub P and Di Giovanni S (2009) A p53-CBP/p300 transcription module is required for GAP-43 expression, axon outgrowth and regeneration. Cell Death Differ. 16(4):543-54
